Accutane (isotretinoin) can be prescribed by your health care provider if you have been diagnosed with nodular acne. However, it should be used only by people to whom it was prescribed as there are a number of dangerous side effects related to the treatment. iPLEDGE is a special program intended for women that are pregnant or breastfeeding to prevent their unborn or nursing babies from being affected by Accutane. If you are not sure about what you are supposed to do under the agreement you sign please talk to your doctor to make sure everything is clear as otherwise dangerous effects may occur.